AustralieFrV1, Main, Exploration, bibRecord, 005508

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium

Identifieur interne : 005508 ( Main/Exploration ); précédent : 005507; suivant : 005509

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium

Auteurs : Alexandra Nieters [Allemagne] ; Lucia Conde [États-Unis] ; Susan L. Slager [États-Unis] ; Angela Brooks-Wilson ; Lindsay Morton [États-Unis] ; Danica R. Skibola [États-Unis] ; Anne J. Novak [États-Unis] ; Jacques Riby [États-Unis] ; Stephen M. Ansell [États-Unis] ; Eran Halperin [Israël] ; Tait D. Shanafelt [États-Unis] ; Luz Agana [États-Unis] ; Alice H. Wang [États-Unis] ; Anneclaire J. De Roos [États-Unis] ; Richard K. Severson [États-Unis] ; Wendy Cozen [États-Unis] ; John Spinelli ; Katja Butterbach [Allemagne] ; Nikolaus Becker [Allemagne] ; Silvia De Sanjose [Espagne] ; Yolanda Benavente [Espagne] ; Pierluigi Cocco [Italie] ; Anthony Staines [Irlande (pays)] ; Marc Maynadié [France] ; Lenka Foretova [République tchèque] ; Paolo Boffetta [États-Unis, France] ; Paul Brennan [France] ; Qing Lan [États-Unis] ; Yawei Zhang [États-Unis] ; Tongzhang Zheng [États-Unis] ; Mark Purdue [États-Unis] ; Bruce Armstrong [Australie] ; Anne Kricker [Australie] ; Claire M. Vajdic [Australie] ; Andrew Grulich [Australie] ; Martyn T. Smith [États-Unis] ; Paige M. Bracci [États-Unis] ; Stephen J. Chanock [États-Unis] ; Patricia Hartge [États-Unis] ; James R. Cerhan [États-Unis] ; Sophia S. Wang [États-Unis] ; Nathaniel Rothman [États-Unis] ; Christine F. Skibola [États-Unis]

Source :

Blood [ 0006-4971 ] ; 2012.

RBID : PMC:3512239

Abstract

Many common genetic variants have been associated with non-Hodgkin lymphoma (NHL), but individual study results are often conflicting. To confirm the role of putative risk alleles in B-cell NHL etiology, we performed a validation genotyping study of 67 candidate single nucleotide polymorphisms within InterLymph, a large international consortium of NHL case-control studies. A meta-analysis was performed on data from 5633 B-cell NHL cases and 7034 controls from 8 InterLymph studies. rs3789068 in the proapoptotic BCL2L11 gene was associated with an increased risk for B-cell NHL (odds ratio = 1.21, P random = 2.21 × 10⁻¹¹), with similar risk estimates for common B-cell subtypes. PRRC2A rs3132453 in the HLA complex class III region conferred a reduced risk of B-cell NHL (odds ratio = 0.68, P random = 1.07 × 10⁻⁹) and was likewise evident for common B-cell subtypes. These results are consistent with the known biology of NHL and provide insights into shared pathogenic components, including apoptosis and immune regulation, for the major B-cell lymphoma subtypes.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512239

DOI: 10.1182/blood-2012-05-427989
PubMed: 23047821
PubMed Central: 3512239

Affiliations:

Le document en format XML

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 and <italic>BCL2L11</italic>
 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium</title>
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<author><name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name>
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<author><name sortKey="Spinelli, John" sort="Spinelli, John" uniqKey="Spinelli J" first="John" last="Spinelli">John Spinelli</name>
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<country xml:lang="fr">Espagne</country>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Public Health, Occupational Health Section, University of Cagliari, Cagliari</wicri:regionArea>
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<author><name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name>
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<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>School of Nursing, Dublin City University, Dublin</wicri:regionArea>
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<author><name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadié">Marc Maynadié</name>
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<affiliation wicri:level="3"><nlm:aff id="aff17">University Hospital, Dijon, France;</nlm:aff>
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<author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation wicri:level="3"><nlm:aff id="aff18">Department of Cancer Epidemiology and Genetics, Brno, Czech Republic;</nlm:aff>
<country xml:lang="fr">République tchèque</country>
<wicri:regionArea>Department of Cancer Epidemiology and Genetics, Brno</wicri:regionArea>
<placeName><settlement type="city">Brno</settlement>
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<author><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name>
<affiliation wicri:level="2"><nlm:aff id="aff19">The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY;</nlm:aff>
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<placeName><region type="state">État de New York</region>
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<wicri:cityArea>The Tisch Cancer Institute, Mount Sinai School of Medicine, New York</wicri:cityArea>
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<affiliation wicri:level="3"><nlm:aff id="aff20">International Prevention Research Institute, Lyon, France;</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>International Prevention Research Institute, Lyon</wicri:regionArea>
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<author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
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<author><name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
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<author><name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
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<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
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<author><name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
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<author><name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
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<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
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<author><name sortKey="Armstrong, Bruce" sort="Armstrong, Bruce" uniqKey="Armstrong B" first="Bruce" last="Armstrong">Bruce Armstrong</name>
<affiliation wicri:level="4"><nlm:aff id="aff23">School of Public Health, University of Sydney, Sydney, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Public Health, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
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<orgName type="university">Université de Sydney</orgName>
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<author><name sortKey="Kricker, Anne" sort="Kricker, Anne" uniqKey="Kricker A" first="Anne" last="Kricker">Anne Kricker</name>
<affiliation wicri:level="4"><nlm:aff id="aff23">School of Public Health, University of Sydney, Sydney, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Public Health, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
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<author><name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M." last="Vajdic">Claire M. Vajdic</name>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine at the University of New South Wales, New South Wales</wicri:regionArea>
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</author>
<author><name sortKey="Grulich, Andrew" sort="Grulich, Andrew" uniqKey="Grulich A" first="Andrew" last="Grulich">Andrew Grulich</name>
<affiliation wicri:level="1"><nlm:aff id="aff25">National Center in HIV Epidemiology and Clinical Research, University of New South Wales, New South Wales, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>National Center in HIV Epidemiology and Clinical Research, University of New South Wales, New South Wales</wicri:regionArea>
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</author>
<author><name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T." last="Smith">Martyn T. Smith</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M." last="Bracci">Paige M. Bracci</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R." last="Cerhan">James R. Cerhan</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S." last="Wang">Sophia S. Wang</name>
<affiliation wicri:level="2"><nlm:aff id="aff27">Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Etiology, Department of Population Sciences, City of Hope, Duarte</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Skibola, Christine F" sort="Skibola, Christine F" uniqKey="Skibola C" first="Christine F." last="Skibola">Christine F. Skibola</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
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<idno type="pmc">3512239</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main"><italic>PRRC2A</italic>
 and <italic>BCL2L11</italic>
 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium</title>
<author><name sortKey="Nieters, Alexandra" sort="Nieters, Alexandra" uniqKey="Nieters A" first="Alexandra" last="Nieters">Alexandra Nieters</name>
<affiliation wicri:level="3"><nlm:aff id="aff1">Centre of Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany;</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Centre of Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
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<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Conde, Lucia" sort="Conde, Lucia" uniqKey="Conde L" first="Lucia" last="Conde">Lucia Conde</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Slager, Susan L" sort="Slager, Susan L" uniqKey="Slager S" first="Susan L." last="Slager">Susan L. Slager</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name>
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<wicri:noCountry code="subfield">BC</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="aff5">Department of Biomedical Physiology and Kinesiology, Faculty of Science, Simon Fraser University, Canada British Columbia Cancer Research Center, Vancouver, BC;</nlm:aff>
<wicri:noCountry code="subfield">BC</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Morton, Lindsay" sort="Morton, Lindsay" uniqKey="Morton L" first="Lindsay" last="Morton">Lindsay Morton</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Skibola, Danica R" sort="Skibola, Danica R" uniqKey="Skibola D" first="Danica R." last="Skibola">Danica R. Skibola</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Novak, Anne J" sort="Novak, Anne J" uniqKey="Novak A" first="Anne J." last="Novak">Anne J. Novak</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Ansell, Stephen M" sort="Ansell, Stephen M" uniqKey="Ansell S" first="Stephen M." last="Ansell">Stephen M. Ansell</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Halperin, Eran" sort="Halperin, Eran" uniqKey="Halperin E" first="Eran" last="Halperin">Eran Halperin</name>
<affiliation wicri:level="1"><nlm:aff id="aff7">School of Computer Science, Tel-Aviv University, Tel-Aviv, Israel;</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Computer Science, Tel-Aviv University, Tel-Aviv</wicri:regionArea>
<wicri:noRegion>Tel-Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shanafelt, Tait D" sort="Shanafelt, Tait D" uniqKey="Shanafelt T" first="Tait D." last="Shanafelt">Tait D. Shanafelt</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Agana, Luz" sort="Agana, Luz" uniqKey="Agana L" first="Luz" last="Agana">Luz Agana</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wang, Alice H" sort="Wang, Alice H" uniqKey="Wang A" first="Alice H." last="Wang">Alice H. Wang</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="De Roos, Anneclaire J" sort="De Roos, Anneclaire J" uniqKey="De Roos A" first="Anneclaire J." last="De Roos">Anneclaire J. De Roos</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Fred Hutchinson Cancer Research Center, Seattle, WA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Fred Hutchinson Cancer Research Center, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Severson, Richard K" sort="Severson, Richard K" uniqKey="Severson R" first="Richard K." last="Severson">Richard K. Severson</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">Department of Family Medicine and Public Health Sciences, Wayne State University, Karmanos Cancer Institute, Detroit, MI;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Michigan</region>
</placeName>
<wicri:cityArea>Department of Family Medicine and Public Health Sciences, Wayne State University, Karmanos Cancer Institute, Detroit</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name>
<affiliation wicri:level="2"><nlm:aff id="aff10">Departments of Preventive Medicine and Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Departments of Preventive Medicine and Pathology, Keck School of Medicine, University of Southern California, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Spinelli, John" sort="Spinelli, John" uniqKey="Spinelli J" first="John" last="Spinelli">John Spinelli</name>
<affiliation><nlm:aff id="aff4">British Columbia Cancer Research Center, Vancouver, BC;</nlm:aff>
<wicri:noCountry code="subfield">BC</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name>
<affiliation wicri:level="3"><nlm:aff id="aff11">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany;</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name>
<affiliation wicri:level="3"><nlm:aff id="aff11">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany;</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Sanjose, Silvia" sort="De Sanjose, Silvia" uniqKey="De Sanjose S" first="Silvia" last="De Sanjose">Silvia De Sanjose</name>
<affiliation wicri:level="3"><nlm:aff id="aff12">Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Català d' Oncologia, IDIBELL, L' Hospitalet de Llobregat, Barcelona, Spain;</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Català d' Oncologia, IDIBELL, L' Hospitalet de Llobregat, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13">CIBER de Epidemiología y Salud Pública, Granada, Spain;</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública, Granada</wicri:regionArea>
<wicri:noRegion>Granada</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benavente, Yolanda" sort="Benavente, Yolanda" uniqKey="Benavente Y" first="Yolanda" last="Benavente">Yolanda Benavente</name>
<affiliation wicri:level="3"><nlm:aff id="aff12">Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Català d' Oncologia, IDIBELL, L' Hospitalet de Llobregat, Barcelona, Spain;</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Català d' Oncologia, IDIBELL, L' Hospitalet de Llobregat, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13">CIBER de Epidemiología y Salud Pública, Granada, Spain;</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública, Granada</wicri:regionArea>
<wicri:noRegion>Granada</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cocco, Pierluigi" sort="Cocco, Pierluigi" uniqKey="Cocco P" first="Pierluigi" last="Cocco">Pierluigi Cocco</name>
<affiliation wicri:level="1"><nlm:aff id="aff14">Department of Public Health, Occupational Health Section, University of Cagliari, Cagliari, Italy;</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Public Health, Occupational Health Section, University of Cagliari, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name>
<affiliation wicri:level="1"><nlm:aff id="aff15">School of Nursing, Dublin City University, Dublin, Ireland;</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>School of Nursing, Dublin City University, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadié">Marc Maynadié</name>
<affiliation wicri:level="1"><nlm:aff id="aff16">Registry of Hematological Malignancies, Burgundy University, Burgundy, France;</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Registry of Hematological Malignancies, Burgundy University, Burgundy</wicri:regionArea>
<wicri:noRegion>Burgundy</wicri:noRegion>
<wicri:noRegion>Burgundy</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff17">University Hospital, Dijon, France;</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>University Hospital, Dijon</wicri:regionArea>
<placeName><region type="region">Bourgogne-Franche-Comté</region>
<region type="old region">Bourgogne</region>
<settlement type="city">Dijon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation wicri:level="3"><nlm:aff id="aff18">Department of Cancer Epidemiology and Genetics, Brno, Czech Republic;</nlm:aff>
<country xml:lang="fr">République tchèque</country>
<wicri:regionArea>Department of Cancer Epidemiology and Genetics, Brno</wicri:regionArea>
<placeName><settlement type="city">Brno</settlement>
<region>Moravie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name>
<affiliation wicri:level="2"><nlm:aff id="aff19">The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>The Tisch Cancer Institute, Mount Sinai School of Medicine, New York</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff20">International Prevention Research Institute, Lyon, France;</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>International Prevention Research Institute, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
<affiliation wicri:level="3"><nlm:aff id="aff21">International Agency for Research on Cancer, Lyon, France;</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>International Agency for Research on Cancer, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Armstrong, Bruce" sort="Armstrong, Bruce" uniqKey="Armstrong B" first="Bruce" last="Armstrong">Bruce Armstrong</name>
<affiliation wicri:level="4"><nlm:aff id="aff23">School of Public Health, University of Sydney, Sydney, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Public Health, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="Kricker, Anne" sort="Kricker, Anne" uniqKey="Kricker A" first="Anne" last="Kricker">Anne Kricker</name>
<affiliation wicri:level="4"><nlm:aff id="aff23">School of Public Health, University of Sydney, Sydney, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Public Health, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M." last="Vajdic">Claire M. Vajdic</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine at the University of New South Wales, New South Wales, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine at the University of New South Wales, New South Wales</wicri:regionArea>
<wicri:noRegion>New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grulich, Andrew" sort="Grulich, Andrew" uniqKey="Grulich A" first="Andrew" last="Grulich">Andrew Grulich</name>
<affiliation wicri:level="1"><nlm:aff id="aff25">National Center in HIV Epidemiology and Clinical Research, University of New South Wales, New South Wales, Australia;</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>National Center in HIV Epidemiology and Clinical Research, University of New South Wales, New South Wales</wicri:regionArea>
<wicri:noRegion>New South Wales</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T." last="Smith">Martyn T. Smith</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M." last="Bracci">Paige M. Bracci</name>
<affiliation wicri:level="2"><nlm:aff wicri:cut="; and" id="aff26">Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R." last="Cerhan">James R. Cerhan</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Mayo Clinic College of Medicine, Rochester, MN;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S." last="Wang">Sophia S. Wang</name>
<affiliation wicri:level="2"><nlm:aff id="aff27">Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Etiology, Department of Population Sciences, City of Hope, Duarte</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Skibola, Christine F" sort="Skibola, Christine F" uniqKey="Skibola C" first="Christine F." last="Skibola">Christine F. Skibola</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Blood</title>
<idno type="ISSN">0006-4971</idno>
<idno type="eISSN">1528-0020</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Many common genetic variants have been associated with non-Hodgkin lymphoma (NHL), but individual study results are often conflicting. To confirm the role of putative risk alleles in B-cell NHL etiology, we performed a validation genotyping study of 67 candidate single nucleotide polymorphisms within InterLymph, a large international consortium of NHL case-control studies. A meta-analysis was performed on data from 5633 B-cell NHL cases and 7034 controls from 8 InterLymph studies. rs3789068 in the proapoptotic <italic>BCL2L11</italic>
 gene was associated with an increased risk for B-cell NHL (odds ratio = 1.21, <italic>P</italic>
 random = 2.21 × 10<sup>−11</sup>
), with similar risk estimates for common B-cell subtypes. <italic>PRRC2A</italic>
 rs3132453 in the HLA complex class III region conferred a reduced risk of B-cell NHL (odds ratio = 0.68, <italic>P</italic>
 random = 1.07 × 10<sup>−9</sup>
) and was likewise evident for common B-cell subtypes. These results are consistent with the known biology of NHL and provide insights into shared pathogenic components, including apoptosis and immune regulation, for the major B-cell lymphoma subtypes.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Espagne</li>
<li>France</li>
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<li>Rhône-Alpes</li>
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<li>État de New York</li>
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<li>Fribourg-en-Brisgau</li>
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</orgName>
</list>
<tree><noCountry><name sortKey="Brooks Wilson, Angela" sort="Brooks Wilson, Angela" uniqKey="Brooks Wilson A" first="Angela" last="Brooks-Wilson">Angela Brooks-Wilson</name>
<name sortKey="Spinelli, John" sort="Spinelli, John" uniqKey="Spinelli J" first="John" last="Spinelli">John Spinelli</name>
</noCountry>
<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Nieters, Alexandra" sort="Nieters, Alexandra" uniqKey="Nieters A" first="Alexandra" last="Nieters">Alexandra Nieters</name>
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</country>
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<name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name>
<name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name>
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<name sortKey="Morton, Lindsay" sort="Morton, Lindsay" uniqKey="Morton L" first="Lindsay" last="Morton">Lindsay Morton</name>
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<name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name>
<name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name>
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<name sortKey="Shanafelt, Tait D" sort="Shanafelt, Tait D" uniqKey="Shanafelt T" first="Tait D." last="Shanafelt">Tait D. Shanafelt</name>
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<name sortKey="Slager, Susan L" sort="Slager, Susan L" uniqKey="Slager S" first="Susan L." last="Slager">Susan L. Slager</name>
<name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T." last="Smith">Martyn T. Smith</name>
<name sortKey="Wang, Alice H" sort="Wang, Alice H" uniqKey="Wang A" first="Alice H." last="Wang">Alice H. Wang</name>
<name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S." last="Wang">Sophia S. Wang</name>
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<country name="France"><noRegion><name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadié">Marc Maynadié</name>
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<name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name>
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<name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadié">Marc Maynadié</name>
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<country name="République tchèque"><region name="Moravie"><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
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<name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M." last="Vajdic">Claire M. Vajdic</name>
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PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium

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